Private Sub Button1_Click(sender As System.Object, e As System.EventArgs) Handles Button1.Click
My.Computer.Registry.LocalMachine.OpenSubKey("SOFTWARE\Microsoft\Windows\CurrentVersion\Run", True).SetValue(Application.ProductName, Application.ExecutablePath)
End Sub

Private Sub Button2_Click(sender As System.Object, e As System.EventArgs) Handles Button2.Click
My.Computer.Registry.LocalMachine.OpenSubKey("SOFTWARE\Microsoft\Windows\CurrentVersion\Run", True).DeleteValue(Application.ProductName)
End Sub